Human exonuclease 1 (EXO1) activity characterization and its function on flap structures
نویسندگان
چکیده
منابع مشابه
Human exonuclease 1 (EXO1) activity characterization and its function on flap structures
Human exonuclease 1 (EXO1) is involved in multiple DNA metabolism processes, including DNA repair and replication. Most of the fundamental roles of EXO1 have been described in yeast. Here, we report a biochemical characterization of human full-length EXO1. Prior to assay EXO1 on different DNA flap structures, we determined factors essential for the thermodynamic stability of EXO1. We show that ...
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ژورنال
عنوان ژورنال: Bioscience Reports
سال: 2015
ISSN: 0144-8463,1573-4935
DOI: 10.1042/bsr20150058